Chrysobactin siderophores produced by Dickeya chrysanthemi EC16

J Nat Prod. 2011 May 27;74(5):1207-12. doi: 10.1021/np200126z. Epub 2011 May 5.

Abstract

The plant pathogen Dickeya chrysanthemi EC16 (formerly known as Petrobacterium chrysanthemi EC16 and Erwinia chrysanthemi EC16) was found to produce a new triscatecholamide siderophore, cyclic trichrysobactin, the related catecholamide compounds, linear trichrysobactin and dichrysobactin, and the previously reported monomeric siderophore unit, chrysobactin. Chrysobactin is comprised of L-serine, D-lysine, and 2,3-dihydroxybenzoic acid (DHBA). Trichrysobactin is a cyclic trimer of chrysobactin joined by a triserine lactone backbone. The chirality of the ferric complex of cyclic trichrysobactin is found to be in the Λ configuration, similar to Fe(III)-bacillibactin, which contains a glycine spacer between the DHBA and L-threonine components and is opposite that of Fe(III)-enterobactin, which contains DHBA ligated directly to L-serine.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Dickeya chrysanthemi / chemistry*
  • Dipeptides / chemistry*
  • Dipeptides / isolation & purification*
  • Molecular Structure
  • Plant Diseases / microbiology
  • Siderophores / chemistry*
  • Siderophores / isolation & purification*

Substances

  • Dipeptides
  • Siderophores
  • chrysobactin