Molecular signatures database (MSigDB) 3.0

Bioinformatics. 2011 Jun 15;27(12):1739-40. doi: 10.1093/bioinformatics/btr260. Epub 2011 May 5.


Motivation: Well-annotated gene sets representing the universe of the biological processes are critical for meaningful and insightful interpretation of large-scale genomic data. The Molecular Signatures Database (MSigDB) is one of the most widely used repositories of such sets.

Results: We report the availability of a new version of the database, MSigDB 3.0, with over 6700 gene sets, a complete revision of the collection of canonical pathways and experimental signatures from publications, enhanced annotations and upgrades to the web site.

Availability and implementation: MSigDB is freely available for non-commercial use at

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Databases, Genetic*
  • Genomics
  • Internet
  • Molecular Sequence Annotation