(-)-Bornyl acetate induces autonomic relaxation and reduces arousal level after visual display terminal work without any influences of task performance in low-dose condition

Biomed Res. 2011 Apr;32(2):151-7. doi: 10.2220/biomedres.32.151.


(-)-Bornyl acetate is the main volatile constituent in numerous conifer oils and has a camphoraceous, pine-needle-like odor. It is frequently used as the conifer needle composition in soap, bath products, room sprays, and pharmaceutical products. However, the psychophysiological effects of (-)-bornyl acetate remained unclear. We investigated the effects of breathing air mixed with (-)-bornyl acetate at different doses (low-dose and high-dose conditions) on the individuals during and after VDT (visual display terminal) work using a visual discrimination task. The amounts of (-)-bornyl acetate through our odorant delivery system for 40 min were 279.4 µg in the low-dose and 716.3 µg in the high-dose (-)-bornyl acetate condition. (-)-Bornyl acetate induced changes of autonomic nervous system for relaxation and reduced arousal level after VDT work without any influences of task performance in low-dose condition, but not in high-dose condition.

MeSH terms

  • Adult
  • Arousal / drug effects*
  • Arousal / physiology
  • Autonomic Nervous System / drug effects*
  • Autonomic Nervous System / physiology
  • Camphanes / pharmacology*
  • Dose-Response Relationship, Drug
  • Electroencephalography
  • Humans
  • Male
  • Odorants
  • Oils, Volatile / chemistry
  • Oils, Volatile / pharmacology*
  • Plant Extracts / chemistry
  • Reaction Time / drug effects*
  • Reaction Time / physiology
  • Relaxation / physiology
  • Relaxation / psychology
  • Task Performance and Analysis
  • Tracheophyta / chemistry
  • Visual Perception / drug effects*
  • Visual Perception / physiology
  • Young Adult


  • Camphanes
  • Oils, Volatile
  • Plant Extracts
  • bornyl acetate