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. 2011 May;29(5):415-20.
doi: 10.1038/nbt.1823.

Minimum Information About a Marker Gene Sequence (MIMARKS) and Minimum Information About Any (X) Sequence (MIxS) Specifications

Pelin Yilmaz  1 Renzo KottmannDawn FieldRob KnightJames R ColeLinda Amaral-ZettlerJack A GilbertIlene Karsch-MizrachiAnjanette JohnstonGuy CochraneRobert VaughanChristopher HunterJoonhong ParkNorman MorrisonPhilippe Rocca-SerraPeter SterkManimozhiyan ArumugamMark BaileyLaura BaumgartnerBruce W BirrenMartin J BlaserVivien BonazziTim BoothPeer BorkFrederic D BushmanPier Luigi ButtigiegPatrick S G ChainEmily CharlsonElizabeth K CostelloHeather Huot-CreasyPeter DawyndtTodd DeSantisNoah FiererJed A FuhrmanRachel E GalleryDirk GeversRichard A GibbsInigo San GilAntonio GonzalezJeffrey I GordonRobert GuralnickWolfgang HankelnSarah HighlanderPhilip HugenholtzJanet JanssonAndrew L KauScott T KelleyJerry KennedyDan KnightsOmry KorenJustin KuczynskiNikos KyrpidesRobert LarsenChristian L LauberTeresa LeggRuth E LeyCatherine A LozuponeWolfgang LudwigDonna LyonsEamonn MaguireBarbara A MethéFolker MeyerBrian MueggeSara NakielnyKaren E NelsonDiana NemergutJosh D NeufeldLindsay K NewboldAnna E OliverNorman R PaceGiriprakash PalanisamyJörg PepliesJoseph PetrosinoLita ProctorElmar PruesseChristian QuastJeroen RaesSujeevan RatnasinghamJacques RavelDavid A RelmanSusanna Assunta-SansonePatrick D SchlossLynn SchrimlRohini SinhaMichelle I SmithErica SodergrenAymé SpoJesse StombaughJames M TiedjeDoyle V WardGeorge M WeinstockDoug WendelOwen WhiteAndrew WhiteleyAndreas WilkeJennifer R WortmanTanya YatsunenkoFrank Oliver Glöckner
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Free PMC article

Minimum Information About a Marker Gene Sequence (MIMARKS) and Minimum Information About Any (X) Sequence (MIxS) Specifications

Pelin Yilmaz et al. Nat Biotechnol. .
Free PMC article

Abstract

Here we present a standard developed by the Genomic Standards Consortium (GSC) for reporting marker gene sequences--the minimum information about a marker gene sequence (MIMARKS). We also introduce a system for describing the environment from which a biological sample originates. The 'environmental packages' apply to any genome sequence of known origin and can be used in combination with MIMARKS and other GSC checklists. Finally, to establish a unified standard for describing sequence data and to provide a single point of entry for the scientific community to access and learn about GSC checklists, we present the minimum information about any (x) sequence (MIxS). Adoption of MIxS will enhance our ability to analyze natural genetic diversity documented by massive DNA sequencing efforts from myriad ecosystems in our ever-changing biosphere.

Figures

Figure 1
Figure 1
Schematic overview about the GSC MIxS standard (brown), including combination with specific environmental packages (blue). Shared descriptors apply to all MIxS checklists; however, each checklist has its own specific descriptors as well. Environmental packages can be applied to any of the checklists. EU, eukarya; BA, bacteria/archaea; PL, plasmid; VI, virus; ORG, organelle.

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