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, 18 (12), 1422-5

Psychogenic Amnesia and Self-Identity: A Multimodal Functional Investigation

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Case Reports

Psychogenic Amnesia and Self-Identity: A Multimodal Functional Investigation

S Arzy et al. Eur J Neurol.

Abstract

Background: Patients with psychogenic amnesia generally suffer from episodic memory deficits associated with an impairment of self-identity. While the first is generally attributed to limbic dysfunction, the latter might be related to posterior parietal cortex.

Methods and results: In a patient with acute repetitive psychogenic amnesia, three different functional investigations (fMRI, electrical-neuroimaging, PET) during both resting-state and a behavioural paradigm testing 'time-travel' showed left posterior parietal activation, unlike in 12 control subjects.

Conclusion: Impairment of self-identity and episodic memory in psychogenic amnesia may be associated with functional alterations of left posterior parietal cortex.

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