This presentation is primarily concerned with the use of sodium diethyldithiocarbamate (Dithiocarb) in the treatment of acute nickel carbonyl poisoning. Reference will be made to earlier studies pertaining to diagnosis in relation to treatment. In addition, recent studies will be briefly considered on the administration of Dithiocarb to rats developing tumors following the muscular implantations of nickel subsulfide (Ni3S2).