Contemporary management of atherosclerotic renovascular disease: before and after ASTRAL

Nephrology (Carlton). 2011 Jul;16(5):457-67. doi: 10.1111/j.1440-1797.2011.01474.x.

Abstract

Atheromatous renovascular disease is an increasingly common diagnosis in our ageing population. Although there is a wide spread of experience in its treatment, the evidence base is heterogeneous and inconclusive. The Angioplasty and Stenting for Renal Artery Lesions trial has provided some, but not all, answers regarding the place of renal revascularization therapy and has also raised more questions and generated further debate. We present a brief review of the significance of atheromatous renovascular disease, discussion of historical treatments, a short analysis of Angioplasty and Stenting for Renal Artery Lesions, and an exploration of where future research lies.

Publication types

  • Review

MeSH terms

  • Angioplasty
  • Atherosclerosis / diagnosis
  • Atherosclerosis / epidemiology
  • Atherosclerosis / therapy*
  • Biomarkers
  • Brachytherapy
  • Embolism / prevention & control
  • Humans
  • Kidney Diseases / diagnosis
  • Kidney Diseases / epidemiology
  • Kidney Diseases / therapy*
  • Prevalence
  • Prognosis
  • Stents*

Substances

  • Biomarkers