CURVES+ web server for analyzing and visualizing the helical, backbone and groove parameters of nucleic acid structures

Nucleic Acids Res. 2011 Jul;39(Web Server issue):W68-73. doi: 10.1093/nar/gkr316. Epub 2011 May 10.


Curves+, a revised version of the Curves software for analyzing the conformation of nucleic acid structures, is now available as a web server. This version, which can be freely accessed at, allows the user to upload a nucleic acid structure file, choose the nucleotides to be analyzed and after optionally setting a number of input variables, view the numerical and graphic results online or download files containing a set of helical, backbone and groove parameters that fully describe the structure. PDB format files are also provided for offline visualization of the helical axis and groove geometry.

MeSH terms

  • Algorithms
  • Base Pairing
  • Nucleic Acid Conformation*
  • Software*
  • User-Computer Interface