Recent US Patterns and Predictors of Prevalent Diabetes among Acute Myocardial Infarction Patients

Abstract

Background. Diabetes mellitus (DM) confers high vascular risk and is a growing national epidemic. We assessed clinical characteristics and prevalence of diagnosed DM among patients hospitalized with acute myocardial infarction (AMI) in the US over the last decade. Methods. Data were obtained from all states within the US that contributed to the Nationwide Inpatient Sample. All patients admitted to hospitals between 1997 and 2006 with a primary discharge diagnosis of AMI were included. Time trends in the proportion of these patients with DM diagnosis were computed. Results. The portion of patients with comorbid diabetes among AMI hospitalizations increased substantially from 18% in 1997 to 30% in 2006 (P < .0001). Absolute numbers of AMI hospitalizations in the US decreased 8% (from 729, 412 to 672, 243), while absolute numbers of AMI hospitalizations with coexisting DM rose 51% ((131, 189 to 198, 044), both (P < .0001). Women with AMI were significantly more likely to have DM than similarly aged men, but these differences diminished with increasing age. Conclusion. Although overall hospitalizations for AMI in the US diminished over the last decade, prevalence of diabetes rose substantially. This may have important consequences for the future societal vascular disease burden.

Figure 1

Overall trends in proportion of patients with a comorbid diagnosis of diabetes among persons hospitalized with acute myocardial infarction (AMI) in the United States (US) population 1997–2006: trend P value <.001.

Figure 2

Overall trends in proportion of patients with a comorbid diagnosis of diabetes by age and sex among persons hospitalized with acute myocardial infarction (AMI) in the United States (US) population 1997–2006. Incident AMI is on the x-axes.