Co-morbidity in a cystic fibrosis population attending a regional clinic

Ir Med J. Nov-Dec 2010;103(10):313-4.


Pulmonary disease remains the major cause of morbidity in patients with cystic fibrosis (CF). However, of 115 patients attending a regional CF clinic we noted 16 cases (14%) with co-morbid conditions. Of this group, 4 of 115 patients (3.5%) had renal problems including both structural and functional defects and 4 (3.5%) had neurological disorders, 3 of which were types of epilepsy. Notably, 3 of 115 patients (2.6%) had different forms of neoplasia, all of which required significant surgical and/or chemotherapeutic intervention. There is now increasing evidence of the association between digestive tract malignancy and CF, which further complicates management of these already complex cases.

MeSH terms

  • Adolescent
  • Adult
  • Child, Preschool
  • Comorbidity
  • Cystic Fibrosis / epidemiology*
  • Female
  • Humans
  • Ireland / epidemiology
  • Kidney Diseases / epidemiology*
  • Male
  • Neoplasms / epidemiology*
  • Nervous System Diseases / epidemiology*
  • Retrospective Studies
  • Young Adult