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, 5 (4), e1135

Chagas Disease Among the Latin American Adult Population Attending in a Primary Care Center in Barcelona, Spain

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Chagas Disease Among the Latin American Adult Population Attending in a Primary Care Center in Barcelona, Spain

Carme Roca et al. PLoS Negl Trop Dis.


Background/aims: The epidemiology of Chagas disease, until recently confined to areas of continental Latin America, has undergone considerable changes in recent decades due to migration to other parts of the world, including Spain. We studied the prevalence of Chagas disease in Latin American patients treated at a health center in Barcelona and evaluated its clinical phase. We make some recommendations for screening for the disease.

Methodology/principal findings: We performed an observational, cross-sectional prevalence study by means of an immunochromatographic test screening of all continental Latin American patients over the age of 14 years visiting the health centre from October 2007 to October 2009. The diagnosis was confirmed by serological methods: conventional in-house ELISA (cELISA), a commercial kit (rELISA) and ELISA using T cruzi lysate (Ortho-Clinical Diagnostics) (oELISA). Of 766 patients studied, 22 were diagnosed with T. cruzi infection, showing a prevalence of 2.87% (95% CI, 1.6-4.12%). Of the infected patients, 45.45% men and 54.55% women, 21 were from Bolivia, showing a prevalence in the Bolivian subgroup (n=127) of 16.53% (95% CI, 9.6-23.39%). ALL THE INFECTED PATIENTS WERE IN A CHRONIC PHASE OF CHAGAS DISEASE: 81% with the indeterminate form, 9.5% with the cardiac form and 9.5% with the cardiodigestive form. All patients infected with T. cruzi had heard of Chagas disease in their country of origin, 82% knew someone affected, and 77% had a significant history of living in adobe houses in rural areas.

Conclusions: We found a high prevalence of T. cruzi infection in immigrants from Bolivia. Detection of T. cruzi-infected persons by screening programs in non-endemic countries would control non-vectorial transmission and would benefit the persons affected, public health and national health systems.

Conflict of interest statement

The authors have declared that no competing interests exist.

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    1. Briceño-Leon R. Chagas disease in the Americas: an ecohealth perspective. Cad Saúde Pública, Rio de Janeiro. 2009;25:S71–S82. - PubMed
    1. Pan American Health Organization. Programa Regional de Chagas de la OPS. Available: Accessed 28 April 2011.
    1. Jackson Y, Angheben A, Carrilero Fernandez B, Jansà i López del Vallado JM, Jannin JG, et al. Prise en charge de la maladie de Chagas en Europe. Expériences et défis en Espagne, Suisse et Italie. Bull Soc Pathol Exot. 2009;102:326–329. - PubMed
    1. Gascón J, Pinazo MJ. Control de la transmisión vertical de Trypanosoma cruzi en España: principal reto de la patología importada. Enferm Infecc Microbiol Clin. 2008;26:605–6. - PubMed
    1. Instituto Nacional de Estadística, España. Available: Accessed 2010 May 26.

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