[Retrospective analysis of the treatment failure of the oral cancer in Department of Otolaryngology and Clinical Oncology University of Medical Sciences in Poznań in the year 2000-2005]

Otolaryngol Pol. 2011 Jan-Feb;65(1):26-32. doi: 10.1016/s0030-6657(11)70624-2.
[Article in Polish]

Abstract

Aim: Retrospective analysis of treatment results in the patients group with oral cancer treated in Department of Otolaryngology and Clinical Oncology K. Marcinkowski University of Medical Sciences in Poznar' between the years 2000-2005. The critical view of the cause of the failure.

Material: The clinical date include: sex, age, stage of the tumor (TNM classification), histological grading, nodes status and 5-years follow up. The parameters were analysed regarding to history of the patients, operative books, outpatients documentation. All parameters were underwent statistical analysis using following tests: Kaplan-Meier, Wilcoxon regarding Gehan and chi2. Date for analysis was classified as ,,end feature" (death or lack of postoperative control) and ,,cut feature" (patient still under control).

Results: Between 2000 and 2005 263 patients were operated due to oral cancer. Only 144 undergo analysis. The rest of 108 patients were calculated as a treatment failure. The middle age was 63 years. There was statistical correlation between tumor stages T (p< or =0.00768), pathological N stage (p< or =0.07225) and 5 year survival. No correlation was found between age, extracapsular spread of the nodes and histopathological grading G and prognosis. In our group 5-years survival present 32% of the patients.

Conclusions: The results of 5-years survival in our patients group are still unsatisfactory. The key lies probably on both side. The first the patients visited doctors still to late with significant advancement of the tumor and second we need better education, introduction of new technologies and shorter time for histological diagnosis and waiting list for post operative radiochemioterapy.

Publication types

  • English Abstract

MeSH terms

  • Academic Medical Centers
  • Adult
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Carcinoma, Squamous Cell / mortality*
  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / therapy*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Mouth Neoplasms / mortality*
  • Mouth Neoplasms / pathology
  • Mouth Neoplasms / therapy*
  • Neoplasm Invasiveness
  • Neoplasm Staging
  • Poland / epidemiology
  • Retrospective Studies
  • Sex Distribution
  • Survival Analysis
  • Treatment Failure