Chronic obstructive pulmonary disease case finding in Mexico in an at-risk population

Int J Tuberc Lung Dis. 2011 Jun;15(6):818-23. doi: 10.5588/ijtld.10.0546.

Abstract

Objective: To apply a case-finding strategy in Mexico to identify chronic airway obstruction among individuals with risk factors and/or symptoms compatible with chronic obstructive pulmonary disease (COPD).

Material and methods: Individuals aged ≥ 40 years with known risk factors and/or symptoms compatible with COPD were referred for an interview and spirometry.

Results: Of 2293 subjects included, 472 (20.6%) had a post-bronchodilator forced expiratory volume in one second/forced vital capacity ratio of <70% (for Global Initiative for Chronic Obstructive Lung Disease [GOLD] Stages II-IV, prevalence was 17.1%). Those with airflow obstruction had smoked more cigarettes for more years than subjects without (19 vs. 13 cigarettes/day, P < 0.001, and 32 vs. 23 years, P < 0.001); they also had a more frequent history of exposure to biomass smoke (23.3% vs. 18.3%, P = 0.002). Females were exposed to biomass smoke for more years (24 vs. 19 years; P < 0.0001) and more hours per day than males (6.2 vs. 5.1; P < 0.001). In multiple logistic regression analysis, increasing age, male sex, ever smoking, pack-years of smoking and years of exposure to biomass smoke were significantly associated with COPD prevalence.

Conclusions: Airflow obstruction was identified in one in five of Mexican individuals with risk factors and/or COPD symptoms. Exposure to biomass smoke was significantly associated with the presence of airflow obstruction.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Forced Expiratory Volume
  • Humans
  • Logistic Models
  • Male
  • Mexico / epidemiology
  • Middle Aged
  • Pulmonary Disease, Chronic Obstructive / diagnosis*
  • Pulmonary Disease, Chronic Obstructive / epidemiology*
  • Risk Factors
  • Sex Distribution
  • Smoking / adverse effects
  • Smoking / epidemiology
  • Smoking Cessation / statistics & numerical data
  • Spirometry
  • Surveys and Questionnaires