Oral hypoglycemic agents in pregnancy

Jerrie S Refuerzo

doi:10.1016/j.ogc.2011.02.013

Oral hypoglycemic agents in pregnancy

Obstet Gynecol Clin North Am. 2011 Jun;38(2):227-34, ix. doi: 10.1016/j.ogc.2011.02.013.

Author

Jerrie S Refuerzo¹

Affiliation

¹ Division of Maternal Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Texas Health Science Center at Houston, Houston, TX 77030, USA. jerrie.s.refuerzo@uth.tmc.edu

PMID: 21575798
DOI: 10.1016/j.ogc.2011.02.013

Abstract

Multiple studies have been published illustrating the use of oral hypoglycemic agents in pregnancy. Glyburide and metformin have been shown to be as effective as insulin for the treatment of gestational diabetes. Both are safe with breastfeeding. Although both glyburide and metformin appear safe for the treatment of type 2 diabetes mellitus, more studies are needed to support this practice.

MeSH terms

Administration, Oral
Breast Feeding
Diabetes, Gestational / drug therapy*
Female
Glyburide / administration & dosage
Glyburide / adverse effects
Humans
Hypoglycemic Agents / administration & dosage*
Hypoglycemic Agents / adverse effects
Insulin / administration & dosage
Metformin / administration & dosage
Metformin / adverse effects
Pregnancy
Treatment Outcome

Substances

Hypoglycemic Agents
Insulin
Metformin
Glyburide