I transposable elements and I-R hybrid dysgenesis in Drosophila

Trends Genet. 1990 Jan;6(1):16-21. doi: 10.1016/0168-9525(90)90044-7.


I factors, transposable elements related to mammalian LINEs, are responsible for I-R hybrid dysgenesis in Drosophila melanogaster. Although they are not structurally related to retrovirus-like transposable elements, they appear to move around the genome via reverse transcription of a full-length RNA intermediate. The mechanism and control of this process are now being dissected at the molecular level.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Base Sequence
  • DNA Transposable Elements*
  • Drosophila / genetics*
  • Female
  • Hybridization, Genetic
  • Male
  • Molecular Sequence Data
  • Mutation


  • DNA Transposable Elements