[Adiponectin and low cardiometabolic risk in obese women]

Arq Bras Endocrinol Metabol. 2011 Mar;55(2):146-54. doi: 10.1590/S0004-27302011000200007.
[Article in Portuguese]

Abstract

Objective: To investigate the association between elevated levels of plasmatic adiponectin (AdipoQ) and low cardiometabolic risk (CMR) in obese women (O(b)W).

Subjects and methods: Case-control study, matched by age, of 306 O(b)W, BMI > 30 kg/m², with 66 cases (21.6%) - all non-hypertensive, normolipidemic, and non-diabetic - conducted in SUS (Brazil's Public Health System) outpatient referral services for obesity in the City of Salvador, Brazil. Secondary data were collected from medical records; primary and complementary data were obtained from a clinical pathology laboratory. Values of AdipoQ > 10.00 µg/ml (> 3(rd) quartile) were considered elevated. Descriptive, bivariate, and conditional logistic regression analyses were performed.

Results: A statistically significant positive association between low CMR and AdipoQ > 10.00 µg/ml in physically active (AOR = 5.1; CI95%: 1.8-14.3), non-smoking (AOR = 3.6;CI95%: 1.6-8.4) O(b)W was found.

Conclusion: This study suggests that physically active, non-smoking O(b)W, with higher AdipoQ levels, present greater chances of a low CMR. It becomes important to reinforce encouragement of the adoption of healthy behaviors, by means of public policies.

MeSH terms

  • Adiponectin / blood*
  • Adult
  • Aged
  • Blood Glucose / analysis
  • Body Mass Index
  • Case-Control Studies
  • Female
  • Humans
  • Metabolic Syndrome / blood*
  • Middle Aged
  • Obesity / blood
  • Obesity / complications*
  • Risk Assessment
  • Risk Factors

Substances

  • Adiponectin
  • Blood Glucose