Varicella-zoster virus (chickenpox) infection in pregnancy

BJOG. 2011 Sep;118(10):1155-62. doi: 10.1111/j.1471-0528.2011.02983.x. Epub 2011 May 18.


Congenital varicella syndrome, maternal varicella-zoster virus pneumonia and neonatal varicella infection are associated with serious fetomaternal morbidity and, not infrequently, mortality. Vaccination against varicella-zoster virus can prevent the disease, and outbreak control limits the exposure of pregnant women to the infectious agent. Maternal varicella-zoster immunoglobulin administration before rash development, with or without antiviral medication, can modify the progression of the disease.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Chickenpox* / congenital
  • Chickenpox* / prevention & control
  • Female
  • Fetal Diseases / prevention & control
  • Gestational Age
  • Humans
  • Immune Sera / administration & dosage
  • Infant, Newborn
  • Pregnancy
  • Pregnancy Complications, Infectious* / prevention & control
  • Vaccination


  • Immune Sera
  • varicella-zoster immune globulin