Gluten-free diet in nonceliac disease

Nutr Clin Pract. 2011 Jun;26(3):294-9. doi: 10.1177/0884533611405538.


A gluten-free diet (GFD) is commonly recognized as the treatment for celiac disease. It also has been investigated as a treatment option for other medical conditions, including dermatitis herpetiformis, irritable bowel syndrome, neurologic disorders, rheumatoid arthritis, diabetes mellitus, and HIV-associated enteropathy. The strength of the evidence for the use of a GFD in these nonceliac diseases varies, and future research may better define the benefits of a GFD for those conditions with weak existing evidence.

Publication types

  • Review

MeSH terms

  • Arthritis, Rheumatoid / diet therapy
  • Autistic Disorder / diet therapy
  • Celiac Disease / diet therapy*
  • Dermatitis Herpetiformis / diet therapy
  • Diabetes Mellitus / diet therapy
  • Diet, Gluten-Free*
  • HIV Enteropathy / diet therapy
  • Humans
  • Irritable Bowel Syndrome / diet therapy
  • Nervous System Diseases / diet therapy