From efficacy to effectiveness in the face of uncertainty: indication creep and prevention creep

JAMA. 2011 May 18;305(19):2005-6. doi: 10.1001/jama.2011.650.

Authors

Benjamin Djulbegovic¹, Ash Paul

Affiliation

¹ Center for Evidence-based Medicine and Health Outcomes Research, University of South Florida, 12901 Bruce B. Downs Blvd, MDC27, Room 3127/3126, Tampa, FL 33612, USA. bdjulbeg@health.usf.edu

PMID: 21586716
DOI: 10.1001/jama.2011.650

No abstract available

MeSH terms

Biomedical Research
Clinical Trials as Topic*
Comparative Effectiveness Research*
Decision Making
Ethics, Medical
False Negative Reactions
False Positive Reactions
Health Resources / statistics & numerical data
Healthcare Disparities
Humans
Resource Allocation
Social Values
Treatment Outcome
Uncertainty*