Previous studies have gradually clarified the relationship between cancer and blood coagulation disorder and its mechanism. Various studies have also reported the association between lung cancer and coagulation disorder. However, it is rare to measure most hemostasis/coagulation-system test parameters in clinical practice. In this study, we investigated the association of hemostasis/coagulation-system test parameters, such as the prothrombin time (PT), activated partial thromboplastin time (APTT), bleeding time, and platelet count, which are routinely measured as preoperative examination parameters in patients with lung cancer, with the histopathologically evaluated stage of lung cancer. Although the mean values of hemostasis/coagulation-system parameters in all subjects were within the normal ranges, there were significant changes with respect to the clinico-pathological factors, showing a specific tendency. In patients in whom the histopathological stage was advanced, the APTT was prolonged, or the platelet count was increased.