Regional differences in connexin32 and connexin43 messenger RNAs in rat brain

Neurosci Lett. 1990 Apr 6;111(3):297-302. doi: 10.1016/0304-3940(90)90278-h.

Abstract

The regional distribution of gap junction mRNAs was examined in the adult rat brain. The level of connexin43 mRNA is more abundant than connexin32, being homogeneously distributed throughout different regions of brain. In contrast, there is dramatic heterogeneity in the level of connexin32 mRNA, with the highest level in the hindbrain. These results suggest that the gap junction genes are differentially expressed in regions of the adult rat brain.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Blotting, Northern
  • Brain Chemistry*
  • Connexins
  • DNA / analysis
  • Densitometry
  • Humans
  • Membrane Proteins / analysis*
  • RNA Probes
  • RNA, Messenger / analysis*
  • Rats
  • Rats, Inbred Strains

Substances

  • Connexins
  • Membrane Proteins
  • RNA Probes
  • RNA, Messenger
  • DNA