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. 2011 Mar-Apr;33(2):116-22.
doi: 10.1016/j.genhosppsych.2010.12.005. Epub 2011 Jan 31.

Associations between posttraumatic stress disorder and hemoglobin A1(C) in low-income minority patients with diabetes

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Associations between posttraumatic stress disorder and hemoglobin A1(C) in low-income minority patients with diabetes

Samantha A Miller et al. Gen Hosp Psychiatry. 2011 Mar-Apr.

Abstract

Objective: Posttraumatic Stress Disorder (PTSD) is prevalent among low-income minorities and is associated with poorer health. However, the association between PTSD and hemoglobin A1(C) (A1(C)) among patients with diabetes has not been fully described. The objective of this cross-sectional study was to evaluate associations between PTSD and A1(C) among low-income minorities with diabetes.

Method: Adults with diabetes were recruited from a network of primary care clinics. Data were obtained from surveys and electronic medical records. Lifetime PTSD symptoms were assessed using the Structured Clinical Interview-DSM-IV and depressive symptoms with the Patient Health Questionnaire-9. A1(C) was obtained from chart review.

Results: Of 103 adults analyzed, 12% had lifetime full PTSD and 12% had subthreshold PTSD. On backward stepwise logistic regression, patients with any PTSD symptoms were significantly more likely to have an A1(C) >7% compared to patients without symptoms (OR(adj) 2.98, 95% CI 1.04-8.52, P=.04). An A1(C) >7% also was associated with an interaction between PTSD symptoms and longer diabetes duration (P<.05).

Conclusion: In this cohort of low-income minorities with diabetes, lifetime PTSD symptoms were significantly associated with an A1(C) >7%.

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Figures

Fig. 1
Fig. 1
Proportion of patients with A1C ≤7% and >7% according to overall PTSD symptom status and PTSD subgroup. *Overall patients with any PTSD symptoms were significantly more likely to have an A1C >7% compared to those without symptoms, P=.014.
Fig. 2
Fig. 2
Interaction between PTSD symptoms and diabetes duration. Overall an A1C >7% was associated with an interaction between PTSD symptoms and longer diabetes duration, P<.05.

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