Microsatellite Instability, Prognosis and Drug Sensitivity of Stage II and III Colorectal Cancer: More Complexity to the Puzzle

J Natl Cancer Inst. 2011 Jun 8;103(11):841-4. doi: 10.1093/jnci/djr170. Epub 2011 May 19.

Publication types

  • Comment
  • Editorial

MeSH terms

  • Antimetabolites, Antineoplastic / administration & dosage
  • Antimetabolites, Antineoplastic / adverse effects
  • Antimetabolites, Antineoplastic / therapeutic use*
  • Chemotherapy, Adjuvant
  • Colorectal Neoplasms / drug therapy
  • Colorectal Neoplasms / genetics*
  • Colorectal Neoplasms / pathology*
  • Colorectal Neoplasms, Hereditary Nonpolyposis / genetics
  • CpG Islands / genetics
  • DNA Methylation
  • DNA Mismatch Repair / genetics*
  • Disease-Free Survival
  • Fluorouracil / administration & dosage
  • Fluorouracil / adverse effects
  • Fluorouracil / therapeutic use*
  • Gene Silencing
  • Germ-Line Mutation
  • Humans
  • Microsatellite Instability*
  • Neoplasm Staging
  • Predictive Value of Tests
  • Prognosis
  • Randomized Controlled Trials as Topic
  • Treatment Failure

Substances

  • Antimetabolites, Antineoplastic
  • Fluorouracil