[Geroprotective properties of dimebon: morphological characterization of organs and tissues in mice after long-term treatment]

Eksp Klin Farmakol. 2011;74(3):32-4.
[Article in Russian]

Abstract

It has been experimentally established that dimebon reliably increased the average and maximum life span and significantly improved the general state of C57BL/6 female mice. Compared to the control group, the animals of the test group were more active, had better hair (greater number of hair follicles per unit area of histological section of skin), and lower age-related reduction of the body weight.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Body Weight / drug effects*
  • Drug Evaluation
  • Female
  • Histamine Antagonists / adverse effects
  • Histamine Antagonists / pharmacology*
  • Indoles / adverse effects
  • Indoles / pharmacology*
  • Longevity / drug effects*
  • Mice

Substances

  • Histamine Antagonists
  • Indoles
  • latrepirdine