Concentration of bisphenol A in highly consumed canned foods on the U.S. market

J Agric Food Chem. 2011 Jul 13;59(13):7178-85. doi: 10.1021/jf201076f. Epub 2011 Jun 7.


Metal food and drink cans are commonly coated with epoxy films made from phenolic polymers produced from bisphenol A (BPA). It is well established that residual BPA monomer migrates into can contents during processing and storage. While a number of studies have reported BPA concentrations in foods from foreign markets and specialty foods on the U.S. market, very few peer-reviewed data for the BPA concentrations in canned food from the U.S. market were available. This study quantified BPA concentrations in 78 canned and two frozen food products from the U.S. market using an adaptation of a previously reported liquid chromatography-tandem mass spectrometry method. The tested products represented 16 different food types that are from the can food classifications that constitute approximately 65% of U.S. canned food sales and canned food consumption. BPA was detected in 71 of the 78 canned food samples but was not detected in either of the two frozen food samples. Detectable BPA concentrations across all foods ranged from 2.6 to 730 ng/g. Large variations in BPA concentrations were found between different products of the same food type and between different lots of the same product. Given the large concentration ranges, the only distinguishable trend was that fruits and tuna showed the lowest BPA concentrations. Experiments with fortified frozen vegetables and brine solutions, as well as higher BPA concentrations in canned food solids over liquid portions, clearly indicated that BPA partitions into the solid portion of foods.

MeSH terms

  • Benzhydryl Compounds
  • Chromatography, Liquid
  • Food Contamination / analysis*
  • Food Packaging
  • Food, Preserved / analysis*
  • Metals
  • Phenols / analysis*
  • Tandem Mass Spectrometry
  • United States


  • Benzhydryl Compounds
  • Metals
  • Phenols
  • bisphenol A