Late spinal metastases from an isolated pineal region germinoma mimicking a schwannoma

J Clin Neurosci. 2011 Aug;18(8):1126-7. doi: 10.1016/j.jocn.2010.11.030. Epub 2011 May 19.


A 20-year-old male with a prior history of germinoma presented 8 years after the initial diagnosis with progressive lower back pain. The preoperative diagnosis was schwannoma based on the appearances of a tumor in the lumbosacral region on MRI; however, histologically, a germinoma "drop" metastasis was seen. This report emphasizes the need for long-term follow-up in patients with germinoma. In addition, this patient is unusual in that the preoperative assessment favored schwannoma.

Publication types

  • Case Reports

MeSH terms

  • Chorionic Gonadotropin, beta Subunit, Human / cerebrospinal fluid
  • Germinoma / cerebrospinal fluid
  • Germinoma / pathology*
  • Humans
  • Magnetic Resonance Imaging / methods
  • Male
  • Neurilemmoma / physiopathology*
  • Pinealoma / cerebrospinal fluid
  • Pinealoma / pathology*
  • Spinal Cord Neoplasms / cerebrospinal fluid
  • Spinal Cord Neoplasms / secondary*
  • Young Adult
  • alpha-Fetoproteins / cerebrospinal fluid


  • Chorionic Gonadotropin, beta Subunit, Human
  • alpha-Fetoproteins