Bioactive proteins from mushrooms

Biotechnol Adv. Nov-Dec 2011;29(6):667-74. doi: 10.1016/j.biotechadv.2011.05.003. Epub 2011 May 14.


Mushrooms have been used as food or medicine for thousands of years. Due to low-fat content and absence of cholesterol, many mushrooms are excellent sources of protein. There are various mushroom proteins with interesting biological activities, such as lectins, fungal immunomodulatory proteins (FIP), ribosome inactivating proteins (RIP), ribonucleases, laccases, and other proteins, which have become popular sources of natural antitumor, antiviral, antimicrobial, antioxidative, and immunomodulatory agents. The aim of this review is to update the present status of bioactive proteins in mushrooms, and to discuss their biomedical potential and future prospectives.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Agaricales / chemistry*
  • Agaricales / metabolism*
  • Fungal Proteins / chemistry
  • Fungal Proteins / metabolism*
  • Fungal Proteins / pharmacology*


  • Fungal Proteins