Pemphigoid gestationis: pathogenesis and clinical features

Lizbeth R A Intong; Dédée F Murrell

doi:10.1016/j.det.2011.03.002

Pemphigoid gestationis: pathogenesis and clinical features

Dermatol Clin. 2011 Jul;29(3):447-52, ix. doi: 10.1016/j.det.2011.03.002.

Authors

Lizbeth R A Intong¹, Dédée F Murrell

Affiliation

¹ Department of Dermatology, St George Hospital, University of New South Wales, Gray Street, Kogarah, Sydney, NSW 2217, Australia.

PMID: 21605810
DOI: 10.1016/j.det.2011.03.002

Abstract

Pemphigoid gestationis is a rare, autoimmune bullous disease of pregnancy that involves autoantibodies directed against type XVII collagen in the basement membrane zone. This article discusses the immunopathogenesis, diagnostic methods, and clinical features of this fascinating disease.

Publication types

Review

MeSH terms

Female
Humans
Pemphigoid Gestationis / etiology*
Pemphigoid Gestationis / pathology*
Pregnancy
Skin / pathology*