Abstract
The comparative analysis of different protocols of infusion therapy of the hemorrhagic shock stage III was performed. The infusion of the colloid solution of hydroxiethylstarch 200/0.5 and non-balanced crystalloid 0.9% solution of natrium chloride leads to the development of negative changes in homeostasis. Whereas infusion of the 4% solution of the modified gelatin and balanced crystalloid solition (sterofundin) allows to avoid the registered changes in electrolyte and alkaline balance.
MeSH terms
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Adult
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Blood Volume / drug effects
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Crystalloid Solutions
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Emergency Medical Services / methods
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Female
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Fluid Therapy / methods
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Fluid Therapy / standards
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Gelatin* / administration & dosage
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Gelatin* / adverse effects
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Hemorrhage / complications
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Hemorrhage / drug therapy
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Hemorrhage / metabolism
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Hemorrhage / physiopathology
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Homeostasis / drug effects*
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Humans
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Hydroxyethyl Starch Derivatives* / administration & dosage
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Hydroxyethyl Starch Derivatives* / adverse effects
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Hypovolemia / drug therapy
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Hypovolemia / etiology
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Hypovolemia / physiopathology
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Infusions, Intravenous
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Isotonic Solutions* / administration & dosage
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Isotonic Solutions* / adverse effects
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Male
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Plasma Substitutes / administration & dosage
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Plasma Substitutes / adverse effects
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Severity of Illness Index
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Shock, Hemorrhagic* / drug therapy
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Shock, Hemorrhagic* / etiology
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Shock, Hemorrhagic* / metabolism
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Shock, Hemorrhagic* / physiopathology
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Sodium Chloride* / administration & dosage
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Sodium Chloride* / adverse effects
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Treatment Outcome
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Water-Electrolyte Imbalance / drug therapy
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Water-Electrolyte Imbalance / etiology
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Water-Electrolyte Imbalance / metabolism
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Water-Electrolyte Imbalance / physiopathology
Substances
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Crystalloid Solutions
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Hydroxyethyl Starch Derivatives
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Isotonic Solutions
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Plasma Substitutes
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Sodium Chloride
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Gelatin