[Antibiotic prophylaxis in primary and revision hip arthroplasty: what is the evidence?]

Orthopade. 2011 Jun;40(6):520-7. doi: 10.1007/s00132-011-1755-0.
[Article in German]


Advances in the perioperative and postoperative management of total joint replacement have led to a steady decrease in the infection rate, which in the case of total hip replacement presently lies between 0.25 and 1%. Unfortunately there is disparity in current practice nationally and internationally, regarding duration, time of application and choice of antibiotics. Currently there are only Level 1a recommendations for primary hip arthroplasty, whereas, due to the heterogeneity and complexity of most revision cases as well as a lack of randomized controlled trials, antibiotic prophylaxis for hip revision arthroplasty is mostly based on the surgeon's preference. In this article the current literature is reviewed and scientifically sound data and recommendations are summarized.

Publication types

  • Meta-Analysis
  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Arthroplasty, Replacement, Hip / statistics & numerical data*
  • Evidence-Based Medicine
  • Hip Prosthesis / statistics & numerical data*
  • Humans
  • Incidence
  • Prosthesis-Related Infections / drug therapy
  • Prosthesis-Related Infections / epidemiology*
  • Prosthesis-Related Infections / prevention & control*
  • Treatment Outcome


  • Anti-Bacterial Agents