Safety of influenza and H1N1 vaccinations in patients with myasthenia gravis, and patient compliance

Muscle Nerve. 2011 Jun;43(6):893-4. doi: 10.1002/mus.22077.

Abstract

Myasthenia gravis (MG) exacerbations may be triggered by infections.In the winter of 2009/2010, the Israeli Ministry of Health recommended that each individual with a chronic condition be vaccinated against both the seasonal influenza and the H1N1 virus. We examined vaccination practices in 74 MG patients. Only 38 patients (51.4%) received the seasonal influenza vaccine, and 24 (32.4%) received the H1N1 vaccine. No exacerbation of MG was found, and therefore seasonal influenza and H1N1 vaccines seem to be safe in MG.

MeSH terms

  • Aged
  • Chronic Disease
  • Female
  • Humans
  • Influenza A Virus, H1N1 Subtype / immunology*
  • Influenza Vaccines / administration & dosage
  • Influenza Vaccines / adverse effects*
  • Influenza, Human / complications
  • Influenza, Human / etiology*
  • Influenza, Human / prevention & control*
  • Israel / epidemiology
  • Male
  • Mass Vaccination / adverse effects*
  • Middle Aged
  • Myasthenia Gravis / complications
  • Myasthenia Gravis / epidemiology*
  • Myasthenia Gravis / virology
  • Patient Compliance*
  • Risk Assessment / methods
  • Seasons

Substances

  • Influenza Vaccines