Emerging therapies for the treatment of neovascular age related macular degeneration
- PMID: 21609228
- DOI: 10.3109/08820538.2011.570846
Emerging therapies for the treatment of neovascular age related macular degeneration
Abstract
Numerous drugs that show promise in the treatment of neovascular age related macular degeneration are currently being evaluated in early clinical trials. Some of these drugs target the vascular endothelial growth factor pathway while others act on different targets along the angiogenesis cascade. The mechanism of action of these novel therapeutics and the results of early clinical trials will be discussed along with a review of angiogenesis.
Similar articles
-
Ranibizumab therapy for neovascular age-related macular degeneration.N Engl J Med. 2010 Oct 21;363(17):1648-55. doi: 10.1056/NEJMct1000495. N Engl J Med. 2010. PMID: 20961248 Review. No abstract available.
-
Emerging pharmacologic therapies for wet age-related macular degeneration.Ophthalmologica. 2009;223(6):401-10. doi: 10.1159/000228926. Epub 2009 Jul 20. Ophthalmologica. 2009. PMID: 19622904 Review.
-
[Anti VEGF therapy in different forms of wet ARMD].Oftalmologia. 2011;55(4):17-9. Oftalmologia. 2011. PMID: 22642131 Romanian.
-
Intravitreal infliximab in patients with macular degeneration who are nonresponders to antivascular endothelial growth factor therapy.Retina. 2010 Nov-Dec;30(10):1601-8. doi: 10.1097/IAE.0b013e3181e9f942. Retina. 2010. PMID: 21060271
-
Ranibizumab (Lucentis) in neovascular age-related macular degeneration: evidence from clinical trials.Br J Ophthalmol. 2010 Jan;94(1):2-13. doi: 10.1136/bjo.2009.159160. Epub 2009 May 13. Br J Ophthalmol. 2010. PMID: 19443462
Cited by
-
Optical Coherence Tomography Image Classification Using Hybrid Deep Learning and Ant Colony Optimization.Sensors (Basel). 2023 Jul 26;23(15):6706. doi: 10.3390/s23156706. Sensors (Basel). 2023. PMID: 37571490 Free PMC article.
-
Anti-inflammatory activities of Gardenia jasminoides extracts in retinal pigment epithelial cells and zebrafish embryos.Exp Ther Med. 2021 Jul;22(1):700. doi: 10.3892/etm.2021.10132. Epub 2021 May 2. Exp Ther Med. 2021. PMID: 34007309 Free PMC article.
-
Comparison of spectral-domain and high-penetration OCT for observing morphologic changes in age-related macular degeneration and polypoidal choroidal vasculopathy.Graefes Arch Clin Exp Ophthalmol. 2014 Jan;252(1):3-9. doi: 10.1007/s00417-013-2474-5. Epub 2013 Oct 18. Graefes Arch Clin Exp Ophthalmol. 2014. PMID: 24136628
-
The role of CRP and inflammation in the pathogenesis of age-related macular degeneration.Biochem Med (Zagreb). 2012;22(1):39-48. doi: 10.11613/bm.2012.005. Biochem Med (Zagreb). 2012. PMID: 22384518 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources