Hepatitis C virus genotypes in clinical specimens tested at a national reference testing laboratory in the United States

Jeffrey J Germer; Jayawant N Mandrekar; Jordan L Bendel; P Shawn Mitchell; Joseph D C Yao

doi:10.1128/JCM.00457-11

Hepatitis C virus genotypes in clinical specimens tested at a national reference testing laboratory in the United States

J Clin Microbiol. 2011 Aug;49(8):3040-3. doi: 10.1128/JCM.00457-11. Epub 2011 May 25.

Authors

Jeffrey J Germer¹, Jayawant N Mandrekar, Jordan L Bendel, P Shawn Mitchell, Joseph D C Yao

Affiliation

¹ Division of Clinical Microbiology, Mayo Clinic, Su 1-602, 200 First Street SW, Rochester, MN 55905-0002, USA.

Abstract

Hepatitis C virus (HCV) genotype (GT) distribution and frequency were studied among 22,407 unique specimens tested at a national reference testing laboratory. Subjects with HCV GT 3 were younger (P < 0.0001) than those with GT 1, 2, or 4, and the regional frequencies of HCV GT 2 and 3 ranged from 19.9% to 29.2%.

MeSH terms

Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Female
Genotype
Hepacivirus / classification*
Hepacivirus / genetics*
Hepacivirus / isolation & purification
Hepatitis C / epidemiology*
Hepatitis C / virology*
Humans
Male
Middle Aged
Molecular Epidemiology
Prevalence
United States / epidemiology
Young Adult