Mycetoma or synovial sarcoma? A case report with review of the literature

J Foot Ankle Surg. 2011 Sep-Oct;50(5):569-76. doi: 10.1053/j.jfas.2011.04.014. Epub 2011 May 26.

Abstract

Mycetoma, also commonly referred to as Madura foot, is statistically rare in the United States. However, it is endemic to other parts of the world. It is a pseudotumor characterized by a triad of tumefaction, draining sinuses, and grains. Two types exist, with each caused by different groups of organisms that require different treatment approaches. Therefore, the exact diagnosis and culture of the organism is vital to successful treatment outcomes. Synovial sarcoma, in contrast, is a malignancy much more commonly seen in the United States. It is characterized by a well-circumscribed, often palpable, mass that is usually well delineated on magnetic resonance imaging. It has characteristic histologic and genetic features that help distinguish it from other soft tissue masses. We present a case of a soft tissue mass diagnosed in the United States. The patient had several clinical and radiographic features of synovial sarcoma but the histologic outcome was mycetoma. The case is followed by a review of the published data.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Antifungal Agents / therapeutic use
  • Female
  • Foot Dermatoses / diagnosis
  • Foot Dermatoses / microbiology*
  • Foot Dermatoses / therapy
  • Humans
  • Itraconazole / therapeutic use
  • Magnetic Resonance Imaging
  • Malaysia / ethnology
  • Middle Aged
  • Mycetoma / diagnosis*
  • Mycetoma / therapy
  • Sarcoma, Synovial / diagnosis
  • Soft Tissue Neoplasms / diagnosis

Substances

  • Antifungal Agents
  • Itraconazole