The Woven EndoBridge cerebral aneurysm embolization device (WEB II): initial clinical experience

Neuroradiology. 2011 Aug;53(8):599-607. doi: 10.1007/s00234-011-0891-x. Epub 2011 May 27.


Introduction: The Woven Endobridge (WEB II) device (Sequent Medical, Inc., Aliso Viejo, CA, USA) is an intra-saccular, oblate, braided-wire embolization device designed to provide flow disruption at the aneurysm neck-parent artery interface. The purpose of this study was to evaluate the acute and short-term performance of the WEB II device regarding the immediacy, degree, and durability of aneurysm occlusion in two patients.

Methods: The WEB II device was implanted in one patient with an unruptured MCA trifurcation aneurysm and one patient with an unruptured basilar tip aneurysm. The degree of intra-aneurysmal flow disruption was graded based on serial digital subtraction aneurysm angiography performed over 30 min immediately following device implantation and at 8 weeks. Immediate and 8-week post-treatment CT and 3-T MRI studies were also performed.

Results: Delivery and deployment of the WEB II device was technically straightforward and achieved without complications. Neither device required retrieval or repositioning after full deployment. There were no peri-procedural thrombembolic or hemorrhagic complications. In both cases, complete aneurysm occlusion was observed within minutes of device deployment. Short-term angiographic follow-up confirmed stable complete occlusion at 8 weeks.

Conclusion: Early technical and clinical results from the first WEB II cases have been encouraging and suggest that the intra-saccular deployment of self-expanding, compliant, cylindrical, high-density, braided metallic mesh constructs may represent a feasible approach for the endovascular treatment of cerebral aneurysms.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Blood Vessel Prosthesis*
  • Embolization, Therapeutic / instrumentation*
  • Equipment Failure Analysis
  • Female
  • Humans
  • Intracranial Aneurysm / diagnosis*
  • Intracranial Aneurysm / surgery*
  • Male
  • Pilot Projects
  • Prosthesis Design
  • Stents*
  • Treatment Outcome