Controlled growth of nanoparticles from solution with in situ liquid transmission electron microscopy

Nano Lett. 2011 Jul 13;11(7):2809-13. doi: 10.1021/nl201166k. Epub 2011 May 27.


Direct visualization of lead sulfide nanoparticle growth is demonstrated by selectively decomposing a chemical precursor from a multicomponent solution using in situ liquid transmission electron microscopy. We demonstrate reproducible control over growth mechanisms that dictate the final morphology of nanostructures while observing growth in real-time with subnanometer spatial resolution. Furthermore, while an intense electron beam can initiate nanoparticle growth, it is also shown that a laser can trigger the reaction independently of the imaging electrons.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Lasers
  • Lead / chemistry*
  • Microscopy, Electron, Transmission
  • Nanoparticles / chemistry*
  • Nanotechnology
  • Particle Size
  • Solutions
  • Sulfides / chemistry*
  • Surface Properties


  • Solutions
  • Sulfides
  • lead sulfide
  • Lead