Improved synthesis of 2,2'-arylmethylene bis(3-hydroxy-5,5-dimethyl-2-cyclohexene-1-one) derivatives catalyzed by urea under ultrasound

Ji-Tai Li; Yan-Wei Li; Ya-Li Song; Guo-Feng Chen

doi:10.1016/j.ultsonch.2011.05.001

Improved synthesis of 2,2'-arylmethylene bis(3-hydroxy-5,5-dimethyl-2-cyclohexene-1-one) derivatives catalyzed by urea under ultrasound

Ultrason Sonochem. 2012 Jan;19(1):1-4. doi: 10.1016/j.ultsonch.2011.05.001. Epub 2011 May 8.

Authors

Ji-Tai Li¹, Yan-Wei Li, Ya-Li Song, Guo-Feng Chen

Affiliation

¹ College of Chemistry and Environmental Science, Hebei University, Baoding 071002, PR China. lijitai@hbu.cn

PMID: 21622016
DOI: 10.1016/j.ultsonch.2011.05.001

Abstract

Synthesis of 2,2'-arylmethylene bis(3-hydroxy-5,5-dimethyl-2-cyclohexene-1-one) derivatives catalyzed by urea via the condensation of aromatic aldehydes and 5,5-dimethyl-1,3-cyclohexanedione was carried out in 80-98% yields at 50 °C in aqueous media under ultrasound. This method provides several advantages such as environment friendliness, high yields and simple work-up procedure.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aldehydes / chemistry
Catalysis
Cyclohexanones / chemical synthesis*
Cyclohexanones / chemistry
Molecular Structure
Ultrasonics*
Urea / chemistry*

Substances

Aldehydes
Cyclohexanones
2-cyclohexen-1-one
1,3-cyclohexanedione
Urea