Propranolol for infantile haemangiomas: a review

Arch Dis Child. 2011 Sep;96(9):890-3. doi: 10.1136/adc.2010.208884. Epub 2011 May 28.

Abstract

Infantile haemangiomas are the most common benign tumour of infancy. However the majority are self-resolving and only a small minority of cases require treatment, with various different medications being used in the past. Over the last few years, propranolol, a non-selective β-blocker, has become a popular and successful treatment for infantile haemangiomas. However, further research on its safety is needed if it is going to be used more frequently. This article summarises the current literature on propranolol for haemangioma treatment with emphasis on its toxicity and adverse event profile.

Publication types

  • Review

MeSH terms

  • Adrenergic beta-Antagonists / administration & dosage
  • Adrenergic beta-Antagonists / adverse effects
  • Adrenergic beta-Antagonists / therapeutic use*
  • Child, Preschool
  • Drug Administration Schedule
  • Hemangioma / drug therapy*
  • Hemangioma / epidemiology
  • Humans
  • Infant
  • Infant, Newborn
  • Propranolol / administration & dosage
  • Propranolol / adverse effects
  • Propranolol / therapeutic use*
  • Treatment Outcome

Substances

  • Adrenergic beta-Antagonists
  • Propranolol