Intravenous flat-detector CT angiography in acute ischemic stroke management

Neuroradiology. 2012 Apr;54(4):383-91. doi: 10.1007/s00234-011-0893-8. Epub 2011 May 31.


Introduction: In the settings of stroke, a non-invasive high-resolution imaging modality to visualize the arterial intracranial circulation in the interventional lab is a helpful mean to plan the endovascular recanalization procedure. We report our initial experience with intravenously enhanced flat-detector CT (IV FDCT) technology in the detection of obstructed intracranial arteries.

Methods: Fourteen consecutive patients elected for endovascular stroke therapy underwent IV FDCT. The scans were intravenously enhanced and acquired in accordance with the previously calculated bolus arrival time. Images were processed on a commercially available workstation for reconstructions and 3D manipulation. Occlusion level and clot length, the quality of collateral vessels, and the patency of anterior and posterior communicating arteries were assessed.

Results: IV FDCT was performed successfully in all the cases and allowed for clot location and length visualization, assessment of communicating arteries patency, and evaluation of vessel collateral grade. Information obtained from this technique was considered useful for patients treated by endovascular approach. Retrospective review of the images by two independent readers was considered accurate and reproducible.

Conclusions: IV FDCT technology provided accurate delineation of obstructed vessel segments in acute ischemic stroke disease. It gave a significant help in the interventional strategy. This new technology available in the operating room might provide a valuable tool in emerging endovascular stroke therapy.

MeSH terms

  • Aged
  • Brain Ischemia / diagnostic imaging*
  • Brain Ischemia / therapy*
  • Cerebral Angiography / methods*
  • Contrast Media
  • Female
  • Humans
  • Imaging, Three-Dimensional / methods
  • Iopamidol
  • Magnetic Resonance Angiography
  • Male
  • Radiographic Image Interpretation, Computer-Assisted
  • Stroke / diagnostic imaging*
  • Stroke / therapy*
  • Tomography, X-Ray Computed / methods*
  • Treatment Outcome
  • X-Ray Intensifying Screens*


  • Contrast Media
  • Iopamidol