Life-style and genital human papillomavirus in a cross-sectional survey in Shanxi Province, China

Asian Pac J Cancer Prev. 2011;12(3):781-6.


Background: To determine the age-stratified HPV prevalence rate and the risk factors of life-style associated with HPV infection among women in rural China.

Methods: An age-stratified, cross-sectional survey of 941 women between 16-59 years old was conducted in rural China. Carcinogenic HPV infection was determined using Digene's Hybrid Capture II HPV DNA test and interviews of life-style were conducted. Odds ratios (OR) and 95% confidence interval (CI) from the logistic regression models were used to determine the risk factors associated with HPV.

Results: Among 941 women, 745 who had sexual intercourse underwent a cervical examination. The prevalence rate of 13 carcinogenic HPV infections among women 20-59 years old was 15.97%. the rate of HPV prevalence in the 25-34 age group was statistically lower than that in 20-24 and 35-59 age groups (X²=13.3, P=0.0013). The OR of bathing every 7-19 days, 20-180 days, less than once every 180 days vs. bathing at least once a week were 1.19, 1.83 and 2.29 respectively and they had a dose-response relationship (Trend Test: P=0.003). The OR of women aged 25-34 age group vs. 20-24 age group was 0.40 (0.16 - 0.97) and the OR of bathing once every 180 days or less vs. at least once weekly was 2.22 (1.14 - 4.33) adjusted for the other confounding factors,.

Conclusions: The HPV prevalence rate was lowest among child bearing women aged 25-34 year. Also, personal hygiene is significantly associated with the HPV infection in this area, regardless of age.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Cervix Uteri
  • China / epidemiology
  • Cross-Sectional Studies
  • DNA, Viral
  • Female
  • Humans
  • Life Style*
  • Male
  • Middle Aged
  • Papillomaviridae / isolation & purification*
  • Papillomavirus Infections / epidemiology
  • Papillomavirus Infections / etiology*
  • Prevalence
  • Risk Factors
  • Rural Population
  • Sexual Behavior
  • Tumor Virus Infections / epidemiology
  • Tumor Virus Infections / etiology*
  • Uterine Cervical Neoplasms / epidemiology
  • Uterine Cervical Neoplasms / etiology*
  • Young Adult


  • DNA, Viral