Acute pancreatitis: a rare complication of acute hepatitis E

J Clin Virol. 2011 Jul;51(3):202-4. doi: 10.1016/j.jcv.2011.04.009. Epub 2011 May 31.


Hepatitis E is an emerging imported disease in Europa but autochthonous cases are described for some years. Extra-hepatic associated manifestations are published. We report a case of acute necrotizing pancreatitis associated with imported acute viral E hepatitis (genotype 1a) in a 26 years old French man travelling and originated from Pakistan. The outcome is favourable spontaneously in two months. This life-threatening hepatitis E related complication is unknown in Europa where genotype 3 virus strains prevail. The clinical presentation is stereotyped with the onset of pancreatitis in the second or third weeks of hepatitis evolution in an Indian male in his second or third decade infected with genotype 1 strain. No pancreatitis-related death is reported in the 13 previous reported cases.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • France
  • Hepatitis Antibodies / blood
  • Hepatitis E / complications*
  • Humans
  • Immunoglobulin G / blood
  • Male
  • Pakistan
  • Pancreatitis, Acute Necrotizing / diagnosis*
  • Pancreatitis, Acute Necrotizing / pathology*
  • RNA, Viral / blood
  • Time Factors
  • Travel*
  • Treatment Outcome


  • Hepatitis Antibodies
  • Immunoglobulin G
  • RNA, Viral