The Methylation Effect in Medicinal Chemistry

Chem Rev. 2011 Sep 14;111(9):5215-46. doi: 10.1021/cr200060g. Epub 2011 Jun 1.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amino Acids / chemistry
  • Chemistry, Pharmaceutical* / methods
  • Drug Design
  • Hydrophobic and Hydrophilic Interactions
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / chemistry
  • Methylation*
  • Pharmaceutical Preparations / chemistry
  • Pharmaceutical Preparations / metabolism*
  • Stereoisomerism

Substances

  • Amino Acids
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Pharmaceutical Preparations