Long-term results after aortic valve-sparing operation (David I)

Eur J Cardiothorac Surg. 2012 Jan;41(1):56-61; discussion 61-2. doi: 10.1016/j.ejcts.2011.04.012.

Abstract

Objective: Aortic valve-sparing David procedure has gained broad acceptance. However, few long-term results have been published. We present our results.

Methods: More than 450 David procedures have been performed in our institution so far. Of these, 126 patients were operated between July 1993 and December 2000. Median age was 57 (8-83) years and 46 (36.5%) were female. As many as 26 (20.6%) had Marfan syndrome, 21 (16.7%) had acute aortic dissection type A (AADA) and 67 (53.2%) had additional procedures.

Results: There were six (4.8%) deaths in 30 post-operative period (POD), four of whom had AADA. In the follow-up, there were 32 (25.4%) late deaths, 11 (34.4%) of these were caused by cardiac or underlying disease or op-related. As many as 15 (11.9%) patients were re-operated; six (40%) were Marfan patients and two (13.3%) had early endocarditis. Follow-up echocardiography of 76 (60.3%) event-free patients showed valve insufficiency (AI)≤AI I° in 68 (89.5%) and grade II in 7 (9.2%) patients. Leaflet degeneration due to proposed leaflet contact with the straight Dacron graft was not observed. A total of 36 (47.4%) patients were in New York Heart Association (NYHA) class I, 33 (43.4%) in NYHA II, and five (6.6%) were in class III. During the entire follow-up of 790 patient-years, there was no stroke or major bleeding. Survival at 1, 5 and 10 years was 93%, 85% and 70%, respectively. Freedom from valve replacement at 1, 5 and 10 years was 96%, 91% and 87%, respectively.

Conclusions: Regardless of the underlying pathology, valve-sparing David I procedure has acceptable long-term results. Valve-related complications such as stroke or major bleeding is exceedingly low.

Publication types

  • Evaluation Study

MeSH terms

  • Acute Disease
  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Aneurysm, Dissecting / surgery
  • Aorta / surgery*
  • Aorta, Thoracic / surgery
  • Aortic Aneurysm / surgery
  • Aortic Valve Insufficiency / surgery*
  • Blood Vessel Prosthesis
  • Blood Vessel Prosthesis Implantation / methods*
  • Child
  • Female
  • Follow-Up Studies
  • Humans
  • Kaplan-Meier Estimate
  • Male
  • Marfan Syndrome / surgery
  • Middle Aged
  • Reoperation
  • Treatment Outcome
  • Young Adult