No role for early IGF-1 signalling in stimulating acute 'muscle building' responses

J Physiol. 2011 Jun 1;589(Pt 11):2667-8. doi: 10.1113/jphysiol.2011.207332.

Authors

Nicholas A Burd¹, Daniel W D West, Donny M Camera, Leigh Breen

Affiliation

¹ Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, ON, Canada, L8S 4K1. burdna@mcmaster.ca

No abstract available

Publication types

Comment

MeSH terms

Androstadienes / pharmacology
Animals
Hypertrophy / metabolism*
Insulin-Like Growth Factor I / physiology*
MAP Kinase Signaling System / physiology
Mechanistic Target of Rapamycin Complex 1
Mice
Multiprotein Complexes
Muscle Proteins / biosynthesis
Muscle, Skeletal / metabolism*
Muscle, Skeletal / pathology
Organ Size / physiology
Phosphatidylinositol 3-Kinases / metabolism
Phosphoinositide-3 Kinase Inhibitors
Phosphorylation / drug effects
Phosphorylation / physiology
Proteins / antagonists & inhibitors
Proteins / metabolism
Proto-Oncogene Proteins c-akt / metabolism
Signal Transduction / physiology*
Sirolimus / pharmacology
TOR Serine-Threonine Kinases
Tuberous Sclerosis Complex 2 Protein
Tumor Suppressor Proteins / metabolism
Weight-Bearing / physiology*
Wortmannin

Substances

Androstadienes
Multiprotein Complexes
Muscle Proteins
Phosphoinositide-3 Kinase Inhibitors
Proteins
Tuberous Sclerosis Complex 2 Protein
Tumor Suppressor Proteins
insulin-like growth factor-1, mouse
Insulin-Like Growth Factor I
Mechanistic Target of Rapamycin Complex 1
Proto-Oncogene Proteins c-akt
TOR Serine-Threonine Kinases
Sirolimus
Wortmannin