Mapping of disease-associated variants in admixed populations

Genome Biol. 2011;12(5):223. doi: 10.1186/gb-2011-12-5-223. Epub 2011 May 30.

Abstract

A more refined estimation of ancestry would benefit admixture mapping and association mapping, making disease loci identification in admixed populations more powerful.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, N.I.H., Intramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • African Continental Ancestry Group / genetics*
  • Alleles
  • American Native Continental Ancestry Group / genetics*
  • Cardiovascular Diseases / genetics
  • Chromosome Mapping
  • European Continental Ancestry Group / genetics*
  • Gene Frequency
  • Genetic Markers*
  • Genetic Predisposition to Disease
  • Genetic Variation
  • Genetics, Population / methods*
  • Genomics / methods*
  • Humans
  • Models, Genetic
  • Phylogeny
  • Polymorphism, Single Nucleotide
  • Population Dynamics*
  • Quantitative Trait Loci
  • Virus Diseases / genetics

Substances

  • Genetic Markers