Lidocaine binds with high affinity to peripheral-type benzodiazepine receptors

Eur J Pharmacol. 1990 Apr 25;179(3):473-5. doi: 10.1016/0014-2999(90)90192-9.

Authors

M Clark¹, R M Post

Affiliation

¹ Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892.

PMID: 2163860
DOI: 10.1016/0014-2999(90)90192-9

No abstract available

MeSH terms

Anesthetics, Local / pharmacology
Animals
Benzodiazepinones / metabolism
Binding, Competitive / drug effects
In Vitro Techniques
Lidocaine / metabolism*
Male
Olfactory Bulb / metabolism
Peripheral Nerves / metabolism*
Rats
Rats, Inbred Strains
Receptors, GABA-A / metabolism*
Valproic Acid / pharmacology

Substances

Anesthetics, Local
Benzodiazepinones
Receptors, GABA-A
4'-chlorodiazepam
Valproic Acid
Lidocaine