High sensitivity troponin T concentrations in patients undergoing noncardiac surgery: a prospective cohort study

Clin Biochem. 2011 Aug;44(12):1021-4. doi: 10.1016/j.clinbiochem.2011.05.017. Epub 2011 May 24.


Objectives: To determine the proportion of noncardiac surgery patients exceeding the published 99th percentile or change criteria with the high sensitivity Troponin T (hs-TnT) assay.

Design and methods: We measured hs-TnT preoperatively and postoperatively on days 1, 2 and 3 in 325 adults.

Results: Postoperatively 45% (95% CI: 39-50%) of patients had hs-TnT≥14ng/L and 22% (95% CI:17-26%) had an elevation (≥14ng/L) and change (>85%) in hs-TnT.

Conclusion: Further research is needed to inform the optimal hs-TnT threshold and change in this setting.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Cohort Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Postoperative Period*
  • Preoperative Period*
  • Surgical Procedures, Operative
  • Troponin T / blood*


  • Troponin T