Isolated right atrial metastasis of malignant melanoma mimicking a myxoma

Hellenic J Cardiol. 2011 May-Jun;52(3):281-4.


Malignant melanoma is the malignancy with the highest propensity for cardiac metastasis. Metastasis to the heart usually occurs in the setting of disseminated disease and is therefore commonly associated with a poor prognosis. We report the case of a 51-year-old woman with a previous history of cutaneous malignant melanoma who presented with a symptomatic, isolated right atrial metastasis attached via a narrow stalk to the interatrial septum, thus resembling a myxoma. The lesion was completely resected, rendering the patient symptom and, potentially, disease-free. The case illustrates the importance of cardiac evaluation in the management of patients with melanoma.

Publication types

  • Case Reports

MeSH terms

  • Diagnosis, Differential
  • Echocardiography, Transesophageal
  • Female
  • Heart Atria / pathology
  • Heart Neoplasms / secondary*
  • Heart Neoplasms / surgery
  • Humans
  • Melanoma / secondary*
  • Melanoma / surgery
  • Middle Aged
  • Myxoma / diagnosis*
  • Skin Neoplasms / pathology*
  • Skin Neoplasms / surgery