Palladium-catalysed hydroxylation and alkoxylation

Chem Soc Rev. 2011 Oct;40(10):4912-24. doi: 10.1039/c1cs15085e. Epub 2011 Jun 6.


The formation of oxygen-carbon bonds is one of the fundamental transformations in organic synthesis. In this regard the application of palladium-based catalysts has been extensively studied during recent years. Nowadays it is an established methodology and the success has been proven in manifold synthetic procedures. This tutorial review summarizes the advances on palladium-catalysed C-O bond formation, means hydroxylation and alkoxylation reactions.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Alcohols / chemistry*
  • Alkenes / chemistry
  • Benzene / chemistry
  • Catalysis
  • Hydroxylation
  • Palladium / chemistry*


  • Alcohols
  • Alkenes
  • alkoxyl radical
  • Palladium
  • Benzene