Stem cells and cell therapies in lung biology and lung diseases

Proc Am Thorac Soc. 2011 Jun;8(3):223-72. doi: 10.1513/pats.201012-071DW.


The University of Vermont College of Medicine and the Vermont Lung Center, with support of the National Heart, Lung, and Blood Institute (NHLBI), the Alpha-1 Foundation, the American Thoracic Society, the Emory Center for Respiratory Health,the Lymphangioleiomyomatosis (LAM) Treatment Alliance,and the Pulmonary Fibrosis Foundation, convened a workshop,‘‘Stem Cells and Cell Therapies in Lung Biology and Lung Diseases,’’ held July 26-29, 2009 at the University of Vermont,to review the current understanding of the role of stem and progenitor cells in lung repair after injury and to review the current status of cell therapy approaches for lung diseases. These are rapidly expanding areas of study that provide further insight into and challenge traditional views of the mechanisms of lung repair after injury and pathogenesis of several lung diseases. The goals of the conference were to summarize the current state of the field, discuss and debate current controversies, and identify future research directions and opportunities for both basic and translational research in cell-based therapies for lung diseases.

Publication types

  • Congress
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptive Immunity
  • Animals
  • Bioengineering
  • Clinical Trials as Topic
  • Disease Models, Animal
  • Epithelial Cells / physiology
  • Humans
  • Immunity, Innate
  • Lung / cytology
  • Lung / physiology
  • Lung Diseases / therapy*
  • Regeneration
  • Stem Cell Research / ethics
  • Stem Cells / physiology*
  • Terminology as Topic
  • Tissue Engineering
  • Tissue Scaffolds